Pharmacological Action and Historical Records of Cicada Flower

1. Anti-tumor effect: anti-tumor effect, anti-tumor of cicada flower, prevention of cancer cell spread and metastasis, etc. are achieved by improving the immunity of patients. Lu Di, director of China Cancer Treatment Protection Network and authoritative tumor experts at home and abroad, believe that the root cause of cancer is the decline of patients' immunity. The immune system is the body's own natural barrier, which can produce anti-cancer and other immune protection to maintain the body's physiological balance and stability. For patients receiving radiotherapy and chemotherapy, it can improve the tolerance to the toxicity of radiotherapy and chemotherapy, eliminate the specific pain of cancer, reduce or eliminate the side effects of leukopenia, hair loss, loss of appetite, vomiting and other side effects caused by radiotherapy and chemotherapy, and improve cachexia. Improve the quality of life and prolong life. Polysaccharide (galactomannan) also has anti-tumor effects.

2. Central nervous system regulation: intraperitoneal injection of natural cicada flower or artificial culture dilute alcohol extract in mice with central nervous system effects can significantly reduce their autonomic activities, prolong the sleep time caused by pentobarbital sodium and chloral hydrate, and improve the sleep rate of mice with subthreshold hypnotic pentobarbital sodium. Prolonged the latency time of convulsion in mice delivered by central excitant drug shining and pentylenetetrazol. The chemical stimulation method and hot plate method proved that the analgesic effect of the two is obvious. Intraperitoneal injection to normal and yeast-induced fever rats has a significant cooling effect. Other data further proved that cicada flower and its artificial culture have obvious analgesic, sedative and antipyretic effects.

3. Toxic side effects: Acute toxicity experiments show that: natural cicada flower ethanol extract mice are gavaged with 60 g/kg, observed for 72h, none of the 20 mice died, only the activity of the animals decreased after administration, and all returned to normal after 24h. The LD50 of intraperitoneal injection is 12.5±2.1 g/kg, and the toxic reactions are writhing, decreased activity, dyspnea and death. The subacute toxicity test showed that the three groups of rats were given 1 g/kg,3 g/kg and 9 g/kg respectively by gavage for 28 days. As a result, there were no abnormal changes in blood routine, liver, kidney and electrocardiogram, and no obvious abnormal changes in pathological examination of important organs such as heart, liver, spleen, lung and kidney.

In the Southern and Northern Dynasties (5th century A. D.), Lei Zhi's "Theory on Lei Gong's Cannon" recorded: "All emissons should be made in vain. After harvest, hang it at the east corner of the house, remove the nail soil, boil it in slurry water for a day, till night, bake it, and grind it fine."

The Sui and Tang Dynasties Zhen Quan's "On Medicinal Properties" records: "Its molting shell has a corner on its head, such as a crown, which is called cicada flower, the best. Sweet and cold, non-toxic. Lord child day hanging, convulsions, night crow palpitations."

Song Su Song of the Song Dynasty said in "Tu Jing Materia" that there is a kind of cicada in Shu today. Its molting head has a corner, like a flower crown, which is called cicada."

Tang Shenwei of the Song Dynasty recorded in "Jing Shi Zheng Classes Prepare Urgent Materia Herb": "Cicada flowers are found everywhere, collected in July, and those who give birth to bitter bamboo are good, and the flowers are unearthed"

Ming Dynasty Li Shizhen "Compendium of Materia Medica" (1590) records: "cicada flower can treat epilepsy, night cry heart palpitations, work with cicada slough"

In addition to the above-mentioned classic medical treatises, there are many ancient medical monographs that record the compound of cicada flowers, such as the Song Dynasty "Shengji General Record", "Children's Medicine Certificate Direct Jusa" and so on.